Very little is known about Isaac Lyons. From a family diary, Isaac Lyons was born in Sawfits, Connecticut, a land dispute area now known as Port Chester, Westchester Co., New York. Byram Point, previously ‘Lyon’s Point’ is an area in Port Chester. It is unknown if there is any connection with Isaac Lyons and Lyon’s Point.

Evidence suggests that Isaac Lyons died before 1860. See Sarah Ann Hadley Lyons (wife).

Sarah Ann Hadley Lyons resided with son-in-law & daughter, Detroit (1860); resided with son & daughter-in-law, Detroit (1870). Lyons, Sarah (wid Isaac), bds 80 Pitcher, Detroit (1873).